{"id":5394,"date":"2021-10-08T07:52:50","date_gmt":"2021-10-08T07:52:50","guid":{"rendered":"https:\/\/edwardseducation.com\/edwardsmasters\/?p=5394"},"modified":"2023-04-23T11:35:42","modified_gmt":"2023-04-23T11:35:42","slug":"the-latest-esc-eacts-guidelines-a-focus-on-valve-durability-available-evidence-and-valve-replacement-innovation","status":"publish","type":"post","link":"https:\/\/dev.edwardseducation.com\/edwardsmasters\/the-latest-esc-eacts-guidelines-a-focus-on-valve-durability-available-evidence-and-valve-replacement-innovation\/","title":{"rendered":"The latest ESC\/EACTS Guidelines: A focus on valve durability, available evidence and valve replacement innovation"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"5394\" class=\"elementor elementor-5394\" data-elementor-post-type=\"post\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-6a61ae8 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"6a61ae8\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-cffd12e\" data-id=\"cffd12e\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-1e29a17 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"1e29a17\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-1d9839e\" data-id=\"1d9839e\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-1098305 elementor-widget elementor-widget-text-editor\" data-id=\"1098305\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Prosthetic valve choice and mode of intervention for aortic valve replacement in younger patients have been controversial because of concerns about long-term durability. The 2021 update to the ESC\/EACTS guidelines for the management of valvular heart disease makes recommendations for patients with severe aortic stenosis, based on available evidence and <br \/>valve replacement innovation.<sup>1<\/sup><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-f0a7464\" data-id=\"f0a7464\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-2779b59 elementor-widget elementor-widget-image\" data-id=\"2779b59\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"226\" height=\"226\" src=\"https:\/\/dev.edwardseducation.com\/edwardsmasters\/wp-content\/uploads\/sites\/2\/2021\/09\/09SEPT21_yes-no_0-1.png\" class=\"attachment-full size-full wp-image-5188\" alt=\"\" srcset=\"https:\/\/dev.edwardseducation.com\/edwardsmasters\/wp-content\/uploads\/sites\/2\/2021\/09\/09SEPT21_yes-no_0-1.png 226w, https:\/\/dev.edwardseducation.com\/edwardsmasters\/wp-content\/uploads\/sites\/2\/2021\/09\/09SEPT21_yes-no_0-1-150x150.png 150w\" sizes=\"(max-width: 226px) 100vw, 226px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-874a0c1 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"874a0c1\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-abe5567\" data-id=\"abe5567\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-9032706 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"9032706\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-af261e3\" data-id=\"af261e3\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-481966f elementor-widget elementor-widget-text-editor\" data-id=\"481966f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>In patients with severe aortic stenosis, age is now a key determining factor in the initial <br>choice between SAVR or TAVI. This change simplifies the initial patient treatment pathway <br>and preferred mode of intervention for patients with severe aortic stenosis.<\/p>\n<p>The guidelines emphasise that while the durability of surgical bioprosthetic valves <br>beyond&nbsp;10 years is well established, evidence supporting the durability of TAVI valves is <br>more limited.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-2516147\" data-id=\"2516147\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-e4d65ed elementor-widget elementor-widget-image\" data-id=\"e4d65ed\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"853\" height=\"1163\" src=\"https:\/\/dev.edwardseducation.com\/edwardsmasters\/wp-content\/uploads\/sites\/2\/2021\/10\/04OCT21_Summary_0-1.jpg\" class=\"attachment-full size-full wp-image-5413\" alt=\"\" srcset=\"https:\/\/dev.edwardseducation.com\/edwardsmasters\/wp-content\/uploads\/sites\/2\/2021\/10\/04OCT21_Summary_0-1.jpg 853w, https:\/\/dev.edwardseducation.com\/edwardsmasters\/wp-content\/uploads\/sites\/2\/2021\/10\/04OCT21_Summary_0-1-220x300.jpg 220w, https:\/\/dev.edwardseducation.com\/edwardsmasters\/wp-content\/uploads\/sites\/2\/2021\/10\/04OCT21_Summary_0-1-751x1024.jpg 751w, https:\/\/dev.edwardseducation.com\/edwardsmasters\/wp-content\/uploads\/sites\/2\/2021\/10\/04OCT21_Summary_0-1-768x1047.jpg 768w\" sizes=\"(max-width: 853px) 100vw, 853px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-f978266 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"f978266\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-a245a18\" data-id=\"a245a18\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-c6c456c elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"c6c456c\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-0c07388\" data-id=\"0c07388\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-c32d7af elementor-widget elementor-widget-text-editor\" data-id=\"c32d7af\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>As valve durability is a key consideration in younger patients (&lt;75 years) at low surgical risk, SAVR (if feasible) is the preferred treatment option. SAVR is also recommended for patients who are unsuitable for transfemoral TAVI and operable.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-b48c16f\" data-id=\"b48c16f\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-c51c976 elementor-widget elementor-widget-image\" data-id=\"c51c976\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"528\" height=\"410\" src=\"https:\/\/dev.edwardseducation.com\/edwardsmasters\/wp-content\/uploads\/sites\/2\/2021\/09\/inspiris_resilia_valve@2x.png\" class=\"attachment-full size-full wp-image-5347\" alt=\"\" srcset=\"https:\/\/dev.edwardseducation.com\/edwardsmasters\/wp-content\/uploads\/sites\/2\/2021\/09\/inspiris_resilia_valve@2x.png 528w, https:\/\/dev.edwardseducation.com\/edwardsmasters\/wp-content\/uploads\/sites\/2\/2021\/09\/inspiris_resilia_valve@2x-300x233.png 300w\" sizes=\"(max-width: 528px) 100vw, 528px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-216e383 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"216e383\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-90a7e3b\" data-id=\"90a7e3b\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-2340898 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"2340898\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-9de87ac\" data-id=\"9de87ac\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-2291271 elementor-widget elementor-widget-text-editor\" data-id=\"2291271\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>The guidelines recommend TAVI for older patients (\u226575 years) and those who are inoperable or high risk for surgery (particularly if feasible via the transfemoral approach).<\/p><p>SAVR or TAVI are recommended for remaining patients according to individual <br \/>clinical, anatomical and procedural characteristics.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-d88a54b\" data-id=\"d88a54b\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-bc25c60 elementor-widget elementor-widget-image\" data-id=\"bc25c60\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"1800\" height=\"2029\" src=\"https:\/\/dev.edwardseducation.com\/edwardsmasters\/wp-content\/uploads\/sites\/2\/2021\/10\/sapien3-Ultra-valve-6X6-FINAL-FLAT.png\" class=\"attachment-full size-full wp-image-5397\" alt=\"\" srcset=\"https:\/\/dev.edwardseducation.com\/edwardsmasters\/wp-content\/uploads\/sites\/2\/2021\/10\/sapien3-Ultra-valve-6X6-FINAL-FLAT.png 1800w, https:\/\/dev.edwardseducation.com\/edwardsmasters\/wp-content\/uploads\/sites\/2\/2021\/10\/sapien3-Ultra-valve-6X6-FINAL-FLAT-266x300.png 266w, https:\/\/dev.edwardseducation.com\/edwardsmasters\/wp-content\/uploads\/sites\/2\/2021\/10\/sapien3-Ultra-valve-6X6-FINAL-FLAT-908x1024.png 908w, https:\/\/dev.edwardseducation.com\/edwardsmasters\/wp-content\/uploads\/sites\/2\/2021\/10\/sapien3-Ultra-valve-6X6-FINAL-FLAT-768x866.png 768w, https:\/\/dev.edwardseducation.com\/edwardsmasters\/wp-content\/uploads\/sites\/2\/2021\/10\/sapien3-Ultra-valve-6X6-FINAL-FLAT-1363x1536.png 1363w\" sizes=\"(max-width: 1800px) 100vw, 1800px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-c8c99bf elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"c8c99bf\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-a928a68\" data-id=\"a928a68\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-6573420 elementor-widget elementor-widget-heading\" data-id=\"6573420\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">Prosthesis selection: Tissue or mechanical valve?<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-eafcc44 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"eafcc44\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-no\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-99a7fe2\" data-id=\"99a7fe2\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-e5e7b90 elementor-widget elementor-widget-text-editor\" data-id=\"e5e7b90\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>If the Heart Team and patient agree that SAVR is the way forward, the choice between mechanical and biological valves comes to the fore. Key factors for the Heart Team to consider are:<\/p><ul><li>The patient\u2019s life expectancy<\/li><li>Lifestyle and environmental factors<\/li><li>Bleeding and thromboembolic risk related to anticoagulation<\/li><li>Potential for surgical or transcatheter reintervention<\/li><li>Informed patient choice<\/li><\/ul><p><br \/>The evidence continues to support the use of aortic bioprostheses for patients over 65 years of age, but just how durable are bioprostheses?<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-e52748e elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"e52748e\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-df3e02c\" data-id=\"df3e02c\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-f7dbdd9 elementor-widget elementor-widget-heading\" data-id=\"f7dbdd9\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">Latest recommendations are supported by real-world evidence and consistent clinical outcomes<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-9dd997b elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"9dd997b\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-d3c6ff8\" data-id=\"d3c6ff8\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-aede4bc elementor-widget elementor-widget-text-editor\" data-id=\"aede4bc\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Several large, long-term studies have demonstrated the excellent long-term durability of the Carpentier-Edwards PERIMOUNT aortic valve.<sup style=\"font-style: normal;font-weight: 400;font-family: MerriweatherSans\">2\u20139<\/sup><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-ebb0af8 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"ebb0af8\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-a8a2436\" data-id=\"a8a2436\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-a789b70 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"a789b70\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-20ba557\" data-id=\"20ba557\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-a222192 elementor-widget elementor-widget-image\" data-id=\"a222192\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t<figure class=\"wp-caption\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.edwards.com\/gb\/devices\/heart-valves\/aortic-pericardial\" target=\"_blank\">\n\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"476\" height=\"327\" src=\"https:\/\/dev.edwardseducation.com\/edwardsmasters\/wp-content\/uploads\/sites\/2\/2021\/10\/CE-PERIMOUNT_A1sw.png\" class=\"attachment-full size-full wp-image-5398\" alt=\"\" srcset=\"https:\/\/dev.edwardseducation.com\/edwardsmasters\/wp-content\/uploads\/sites\/2\/2021\/10\/CE-PERIMOUNT_A1sw.png 476w, https:\/\/dev.edwardseducation.com\/edwardsmasters\/wp-content\/uploads\/sites\/2\/2021\/10\/CE-PERIMOUNT_A1sw-300x206.png 300w\" sizes=\"(max-width: 476px) 100vw, 476px\" \/>\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<figcaption class=\"widget-image-caption wp-caption-text\"><\/figcaption>\n\t\t\t\t\t\t\t\t\t\t<\/figure>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-7ce922f elementor-widget elementor-widget-text-editor\" data-id=\"7ce922f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p style=\"text-align: center\">Carpentier-Edwards PERIMOUNT valve<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-a4b7004\" data-id=\"a4b7004\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-51d39e8 elementor-widget elementor-widget-text-editor\" data-id=\"51d39e8\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Overall expected valve durability of the PERIMOUNT aortic valve is 19.7 years.<sup>2-4<\/sup><\/p>\n<ul>\n<li>Broken down by age, durability was\n<ul>\n<li>17.6 years for patients aged \u226460 years<\/li>\n<li>19 years for patients aged 50\u201365 years<\/li>\n<li>22.1 years for patients aged 60\u201370 years<\/li>\n<\/ul>\n<\/li>\n<li>Twenty-year probability of explant due to SVD across all age groups is 5.4%<sup>7<\/sup><\/li>\n<li>Younger age at implantation is associated with a higher risk of structural valve deterioration,<sup>2,6-9<\/sup> but durability is good even in these younger patients<sup>2,6-9<\/sup><\/li>\n<\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-8cb406f elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"8cb406f\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-661510e\" data-id=\"661510e\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-a4f05a9 elementor-widget elementor-widget-heading\" data-id=\"a4f05a9\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Recommended resources<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-0747198 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"0747198\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-5adc09f\" data-id=\"5adc09f\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-0e40bea elementor-widget elementor-widget-text-editor\" data-id=\"0e40bea\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><blockquote class=\"wp-embedded-content\" data-secret=\"I009W2uXow\"><a href=\"https:\/\/edwardseducation.com\/edwardsmasters\/trifecta-versus-perimount-magna-ease-aortic-valve-prostheses\/\">Trifecta versus Perimount Magna Ease aortic valve prostheses<\/a><\/blockquote><iframe class=\"wp-embedded-content\" sandbox=\"allow-scripts\" security=\"restricted\" style=\"position: absolute; clip: rect(1px, 1px, 1px, 1px);\" title=\"&#8220;Trifecta versus Perimount Magna Ease aortic valve prostheses&#8221; &#8212; Edwards Masters\" src=\"https:\/\/edwardseducation.com\/edwardsmasters\/trifecta-versus-perimount-magna-ease-aortic-valve-prostheses\/embed\/#?secret=o0Fr8D512P#?secret=I009W2uXow\" data-secret=\"I009W2uXow\" width=\"500\" height=\"282\" frameborder=\"0\" marginwidth=\"0\" marginheight=\"0\" scrolling=\"no\"><\/iframe><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-b87857d elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"b87857d\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-08b1a17\" data-id=\"08b1a17\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-7a31739 elementor-widget elementor-widget-heading\" data-id=\"7a31739\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">References<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-60ece62 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"60ece62\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-8229a53\" data-id=\"8229a53\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-4c54235 elementor-widget elementor-widget-text-editor\" data-id=\"4c54235\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>1. Vahanian A, Beyersdorf F, Praz F<em> et al.<\/em> 2021 ESC\/EACTS Guidelines for the management of valvular heart disease. <em>Eur Heart J<\/em>. 2021<strong>:<\/strong><\/p><p>2. Bourguignon T, Bouquiaux-Stablo A-L, Candolfi P<em> et al.<\/em> Very long-term outcomes of the Carpentier-Edwards Perimount valve in aortic position. <em>Ann Thorac Surg<\/em>. 2015; <strong>99:<\/strong> 831\u20137.<\/p><p>3. Bourguignon T, El Khoury R, Candolfi P<em> et al.<\/em> Very long-term outcomes of the Carpentier-Edwards Perimount aortic valve in patients aged 60 or younger. <em>Ann Thorac Surg<\/em>. 2015; <strong>100:<\/strong> 853\u20139.<\/p><p>4. Bourguignon T, Lhommet P, El Khoury R<em> et al.<\/em> Very long-term outcomes of the Carpentier-Edwards Perimount aortic valve in patients aged 50\u201365 years. <em>Eur J Cardio-Thorac Surg<\/em>. 2016; <strong>49:<\/strong> 1462\u20138.<\/p><p>5. Forcillo J, El Hamamsy I, Stevens LM<em> et al.<\/em> The Perimount valve in the aortic position: Twenty-year experience with patients under 60\u00a0years old. <em>Ann Thorac Surg<\/em>. 2014; <strong>97:<\/strong> 1526\u201332.<\/p><p>6. Forcillo J, Pellerin M, Perrault LP<em> et al.<\/em> Carpentier-Edwards pericardial valve in the aortic position: 25-years experience. <em>Ann Thorac Surg<\/em>. 2013; <strong>96:<\/strong> 486\u201393.<\/p><p>7. Johnston DR, Soltesz EG, Vakil N<em> et al.<\/em> Long-term durability of bioprosthetic aortic valves: Implications from 12,569 implants. <em>Ann Thorac Surg<\/em>. 2015; <strong>99:<\/strong> 1239\u201347.<\/p><p>8. McClure RS, Narayanasamy N, Wiegerinck E<em> et al.<\/em> Late outcomes for aortic valve replacement with the Carpentier-Edwards pericardial bioprosthesis: up to 17-year follow-up in 1,000 patients. <em>Ann Thorac Surg<\/em>. 2010; <strong>89:<\/strong> 1410\u20136.<\/p><p>9. Minakata K, Tanaka S, Okawa Y<em> et al.<\/em> Long-term outcome of the Carpentier-Edwards Pericardial valve in the aortic position in Japanese Patients. <em>Circ J<\/em>. 2014; <strong>78:<\/strong> 882\u20139.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-eeb1608 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"eeb1608\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-no\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-7ee4471\" data-id=\"7ee4471\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-f8f848d elementor-widget elementor-widget-text-editor\" data-id=\"f8f848d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>For professional use. For a listing of indications, contraindications, precautions, warnings, and potential adverse events, please refer to the Instructions for Use (consult eifu.edwards.com where applicable).<\/strong><\/p><p><strong>Edwards devices placed on the European market meeting the essential requirements referred to in Article 3 of the Medical Device Directive 93\/42\/EEC bear the CE marking of conformity.<\/strong><\/p><p><strong>Edwards, Edwards Lifesciences, the stylized E logo, Carpentier-Edwards, Carpentier-Edwards PERIMOUNT, INSPIRIS, INSPIRIS RESILIA, Magna, Magna Ease, PERI, PERIMOUNT, RESILIA and\u00a0SAPIEN are trademarks of Edwards Lifesciences Corporation. All other trademarks are the property of their respective owners.<\/strong><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-33b0e7f elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"33b0e7f\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-562ff2c\" data-id=\"562ff2c\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-a0c9d98 elementor-widget elementor-widget-text-editor\" data-id=\"a0c9d98\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>\u00a9 2021 Edwards Lifesciences Corporation. All rights reserved. PP&#8211;EU-2949 v1.0<\/strong><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-6c519d3 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"6c519d3\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-d209183\" data-id=\"d209183\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-dbc14ac elementor-widget elementor-widget-text-editor\" data-id=\"dbc14ac\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>Edwards Lifesciences<\/strong>\u00a0\u2022 Route de l\u2019Etraz 70, 1260 Nyon, Switzerland \u2022 edwards.com<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Prosthetic valve choice and mode of intervention [&hellip;]<\/p>\n","protected":false},"author":26,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"tags":[],"topic_interest":[450,442],"secondary_topic":[459,467,494,457,493,453],"article_tags":[532,536,613,628,646,652,782,1043,825],"anatomy":[4],"topics":[12],"course":[],"class_list":["post-5394","post","type-post","status-publish","format-standard","hentry","anatomy-aortic","topics-patient-management"],"acf":{"latestnews":false,"mostpopular":false,"views":"320","header__style":"default","header__alternative-title":"","footer-section__show":true,"footer-section__object":false,"slider__background-image":false,"slider_title":"","slider__subtitle":"","time_period":"","MobileLandscapeImage":false,"MobilePortraitImage":false,"PathOrder":"0","slider__background-image_mobile":false,"slider__background-image_tablet":false,"time_period_events":"","MobilePortraitMode_aspect_ratio_3.5":false,"Images_aspect_ratio_4.3":false},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.0 - 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