{"id":7314,"date":"2022-12-06T15:45:40","date_gmt":"2022-12-06T15:45:40","guid":{"rendered":"https:\/\/edwardseducation.com\/edwardsmasters\/?p=7314"},"modified":"2023-04-23T10:59:44","modified_gmt":"2023-04-23T10:59:44","slug":"perimount-magna-ease-vs-inspiris-resilia-valve-in-patients-below-70-years-of-age-a-propensity-matched-analysis-of-the-haemodynamic-performances","status":"publish","type":"post","link":"https:\/\/dev.edwardseducation.com\/edwardsmasters\/perimount-magna-ease-vs-inspiris-resilia-valve-in-patients-below-70-years-of-age-a-propensity-matched-analysis-of-the-haemodynamic-performances\/","title":{"rendered":"PERIMOUNT Magna Ease vs INSPIRIS RESILIA valve in patients below 70 years of age: a propensity-matched analysis of the haemodynamic performances"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"7314\" class=\"elementor elementor-7314\" data-elementor-post-type=\"post\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-63034de elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"63034de\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-b117ae5\" data-id=\"b117ae5\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-b5cca94 elementor-widget elementor-widget-text-editor\" data-id=\"b5cca94\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Francica A, Tonelli F, San Biagio L, Rossetti C, Tropea I, Luciani GB, Faggian G and Onorati F.<\/p><p><em>Presented at 36<\/em><em><sup>th<\/sup><\/em><em>\u00a0<\/em><em>European Association for Cardio-Thoracic Surgery Annual Meeting, 2022.\u00a0\u00a0<\/em><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-14b448c elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"14b448c\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-004bdd5\" data-id=\"004bdd5\" data-element_type=\"column\" data-e-type=\"column\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-8d54873 elementor-widget elementor-widget-heading\" data-id=\"8d54873\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Key points:<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c21ce4f elementor-widget elementor-widget-text-editor\" data-id=\"c21ce4f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<ul><li>The safety and efficacy outcomes of the new INSPIRIS RESILIA valve in patients younger than 70 years were comparable to the established Carpentier-Edwards PERIMOUNT Magna Ease valve at mid-term.<\/li><li>At Year 3, haemodynamic outcomes remained stable and were similar between INSPIRIS RESILIA valve and the comparator.<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-c6d0ee4 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"c6d0ee4\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-fba092c\" data-id=\"fba092c\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-3fa57a0 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"3fa57a0\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-e37ef44\" data-id=\"e37ef44\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-1ba7b63 elementor-widget elementor-widget-heading\" data-id=\"1ba7b63\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Background information<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b09caf5 elementor-widget elementor-widget-text-editor\" data-id=\"b09caf5\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<ul><li>The third-generation PERIMOUNT Magna Ease valve is the gold standard bioprosthesis for patients of all ages.<\/li><li>The INSPIRIS RESILIA valve is a new bovine pericardial valve, and data on its use in patients aged \u226470 years are currently limited.<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-f2d92dc elementor-widget elementor-widget-heading\" data-id=\"f2d92dc\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Aims<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-cb11537 elementor-widget elementor-widget-text-editor\" data-id=\"cb11537\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<ul><li>To compare the haemodynamic performance of the INSPIRIS RESILIA valve <em>vs <\/em>the PERIMOUNT Magna Ease valve in aortic position in patients younger than 70 years who had undergone aortic valve replacement surgery.<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-31df1c1 elementor-widget elementor-widget-heading\" data-id=\"31df1c1\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Type of study<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-90fa600 elementor-widget elementor-widget-text-editor\" data-id=\"90fa600\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<ul><li>A propensity score-matched analysis.<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-60f2cf9 elementor-widget elementor-widget-heading\" data-id=\"60f2cf9\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Endpoints<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-7639f97 elementor-widget elementor-widget-text-editor\" data-id=\"7639f97\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<ul>\n \t<li>The endpoint was haemodynamic performance, including mean pressure gradient, peak velocity (V<sub>max<\/sub>) and the left ventricular end-diastolic volume (LVEDV) at Year 1.<\/li>\n<\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-937e6e2 elementor-widget elementor-widget-heading\" data-id=\"937e6e2\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Methods<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-86b7569 elementor-widget elementor-widget-text-editor\" data-id=\"86b7569\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<ul><li>The study included patients aged <u>&lt;<\/u>70 years who received an INSPIRIS RESILIA valve between 2017 and 2022 or a PERIMOUNT Magna Ease valve between 2010 and 2012.<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-06fae8a\" data-id=\"06fae8a\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-5bf2411 elementor-widget elementor-widget-text-editor\" data-id=\"5bf2411\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<ul><li>Propensity score-matching was used to account for differences in baseline characteristics, including age, diabetes, hypertension, dyslipidaemia, atrial fibrillation, bicuspid valve and moderate\u2013severe aortic regurgitation.<\/li><li>Patients underwent follow-up examination with echocardiography 1 year after surgery.<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-9617afb elementor-widget elementor-widget-heading\" data-id=\"9617afb\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Results<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-abbe715 elementor-widget elementor-widget-text-editor\" data-id=\"abbe715\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><b>Patients<\/b><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-eee41bb elementor-widget elementor-widget-text-editor\" data-id=\"eee41bb\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<ul><li>The study included 238 patients with PERIMOUNT Magna Ease valve and 192 with INSPIRIS RESILIA valve; 122 of each group were included in the propensity score-matched analysis.<\/li><\/ul><ul><li>In the propensity-matched cohort, the mean age was 7 \u00b1 11.1 years in the PERIMOUNT Magna Ease group and 57.0 \u00b1 9.1 years in the INSPIRIS RESILIA group (p=0.098); 19.7% of patients in the PERIMOUNT Magna Ease group and 25.4% of patients in the INSPIRIS RESILIA group were female (p=0.284). EuroSCORE II was 2.7 \u00b1 2.4% in both groups (p=0.788).<\/li><\/ul><ul><li>Periprocedural outcomes were similar and not statistically significant between INSPIRIS RESILIA and PERIMOUNT Magna Ease valves.<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-499959d elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"499959d\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-76c77b1\" data-id=\"76c77b1\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-8f8e7f6 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"8f8e7f6\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-f2ce6a1\" data-id=\"f2ce6a1\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-3b5d5b5 elementor-widget elementor-widget-text-editor\" data-id=\"3b5d5b5\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>Table 1. Periprocedural outcomes<\/strong><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2a9f139 elementor-widget elementor-widget-image\" data-id=\"2a9f139\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"451\" height=\"300\" src=\"https:\/\/dev.edwardseducation.com\/edwardsmasters\/wp-content\/uploads\/sites\/2\/2022\/12\/P10.jpg\" class=\"attachment-2048x2048 size-2048x2048 wp-image-7441\" alt=\"\" srcset=\"https:\/\/dev.edwardseducation.com\/edwardsmasters\/wp-content\/uploads\/sites\/2\/2022\/12\/P10.jpg 451w, https:\/\/dev.edwardseducation.com\/edwardsmasters\/wp-content\/uploads\/sites\/2\/2022\/12\/P10-300x200.jpg 300w\" sizes=\"(max-width: 451px) 100vw, 451px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3f60970 elementor-widget elementor-widget-text-editor\" data-id=\"3f60970\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><b>Haemodynamic performance<\/b><\/p><ul><li>At 1 and 3 years, the differences in mean pressure gradient, V<sub>max<\/sub> or LVEDV (Figure 1) with the INSPIRIS RESILIA valve vs the Magna Ease valve did not reach statistical significance. Mean gradients and peak velocity was also similar between groups across different valve sizes (19\u201321 mm, 23\u201325 mm and 27\u201329 mm).<\/li><\/ul><ul><li>At 3 years, there was no reports of structural valve deterioration in the INSPIRIS RESILIA valves; four cases were reported in the PERIMOUNT Magna Ease valve, with 2 patients experiencing moderate\u2013severe aortic stenosis and two patients reporting moderate\u2013severe regurgitation.<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-16024cd\" data-id=\"16024cd\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-20f434d elementor-widget elementor-widget-heading\" data-id=\"20f434d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Conclusion<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b984fc9 elementor-widget elementor-widget-text-editor\" data-id=\"b984fc9\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>The safety and efficacy outcomes of the new INSPIRIS RESILIA valve in patients younger than 70 years were comparable to the excellent outcomes in the established PERIMOUNT Magna Ease valve. Both valves also showed stable and comparable haemodynamics at short- to mid-term follow-up. These results may even suggest improved long-term outcomes in younger patients receiving the INSPIRIS RESILIA valve, however, more studies are needed to establish the potential advantages of this valve.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-975e666 elementor-widget elementor-widget-text-editor\" data-id=\"975e666\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><em>This document is a summary of the Francica A <\/em>et al. <em>presentation and covers key information including aim, type of study, methods, results and conclusions.<\/em><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-cd6b5c4 elementor-widget elementor-widget-heading\" data-id=\"cd6b5c4\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">The full publication is available at:<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-0540cf5 elementor-widget elementor-widget-text-editor\" data-id=\"0540cf5\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"color: #000000\"><strong><a style=\"color: #000000\" href=\"https:\/\/bit.ly\/Francica2022\">https:\/\/bit.ly\/Francica2022<\/a><\/strong><\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-6090034 elementor-widget elementor-widget-heading\" data-id=\"6090034\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Abbreviations:<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-e049bcf elementor-widget elementor-widget-image\" data-id=\"e049bcf\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"448\" height=\"111\" src=\"https:\/\/dev.edwardseducation.com\/edwardsmasters\/wp-content\/uploads\/sites\/2\/2022\/12\/P12.jpg\" class=\"attachment-large size-large wp-image-7443\" alt=\"\" srcset=\"https:\/\/dev.edwardseducation.com\/edwardsmasters\/wp-content\/uploads\/sites\/2\/2022\/12\/P12.jpg 448w, https:\/\/dev.edwardseducation.com\/edwardsmasters\/wp-content\/uploads\/sites\/2\/2022\/12\/P12-300x74.jpg 300w\" sizes=\"(max-width: 448px) 100vw, 448px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-737e1e7 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"737e1e7\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-7feb789\" data-id=\"7feb789\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-97008b6 elementor-widget elementor-widget-text-editor\" data-id=\"97008b6\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><b>Figure 1. LVEDV at (A) Year 1 and (B) Year 3<\/b><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-530a5b5 elementor-widget elementor-widget-image\" data-id=\"530a5b5\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"1024\" height=\"308\" src=\"https:\/\/dev.edwardseducation.com\/edwardsmasters\/wp-content\/uploads\/sites\/2\/2022\/12\/P11-1024x308.jpg\" class=\"attachment-large size-large wp-image-7442\" alt=\"\" srcset=\"https:\/\/dev.edwardseducation.com\/edwardsmasters\/wp-content\/uploads\/sites\/2\/2022\/12\/P11-1024x308.jpg 1024w, https:\/\/dev.edwardseducation.com\/edwardsmasters\/wp-content\/uploads\/sites\/2\/2022\/12\/P11-300x90.jpg 300w, https:\/\/dev.edwardseducation.com\/edwardsmasters\/wp-content\/uploads\/sites\/2\/2022\/12\/P11-768x231.jpg 768w, https:\/\/dev.edwardseducation.com\/edwardsmasters\/wp-content\/uploads\/sites\/2\/2022\/12\/P11.jpg 1288w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-e2a98eb elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"e2a98eb\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-7eb6cb2\" data-id=\"7eb6cb2\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-92b277b elementor-widget elementor-widget-text-editor\" data-id=\"92b277b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>No clinical data are available that evaluate the long term impact of RESILIA tissue in patients.<\/p><p><strong>Medical<\/strong> <strong>device<\/strong> <strong>for<\/strong> <strong>professional<\/strong> <strong>use.<\/strong> <strong>For<\/strong> <strong>a<\/strong> <strong>listing<\/strong> <strong>of<\/strong> <strong>indications,<\/strong> <strong>contraindications,<\/strong> <strong>precautions,<\/strong> <strong>warnings,<\/strong> <strong>and<\/strong><strong> potential adverse events, please refer to the Instructions for Use (consult eifu.edwards.com where applicable).<\/strong><\/p><p><strong>\u00a0<\/strong>Edwards, Edwards Lifesciences, the stylized E logo, Carpentier-Edwards, Carpentier-Edwards PERIMOUNT, Carpentier-Edwards PERIMOUNT Magna Ease, INSPIRIS, INSPIRIS RESILIA, Magna, Magna Ease, PERI, PERIMOUNT, PERIMOUNT Magna and RESILIA are trademarks or service marks of Edwards Lifesciences Corporation. All other trademarks are the property of their respective owners.<\/p><p>\u00a9 2022 Edwards Lifesciences Corporation. All rights reserved. PP&#8211;EU-5308 v1.0<\/p><p><strong>Edwards<\/strong> <strong>Lifesciences<\/strong> <strong>\u2022<\/strong> Route de l\u2019Etraz 70, 1260 Nyon, Switzerland \u2022 edwards.com<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Francica A, Tonelli F, San Biagio L, [&hellip;]<\/p>\n","protected":false},"author":1869,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"tags":[],"topic_interest":[],"secondary_topic":[],"article_tags":[1224,616,1193,1226],"anatomy":[],"topics":[],"course":[],"class_list":["post-7314","post","type-post","status-publish","format-standard","hentry"],"acf":{"views":"160","latestnews":false,"mostpopular":false,"header__style":"default","header__alternative-title":"","footer-section__show":true,"footer-section__object":false,"PathOrder":"0","slider__background-image":false,"slider__background-image_mobile":false,"slider__background-image_tablet":false,"slider_title":"","slider__subtitle":"","time_period":"","time_period_events":"","MobileLandscapeImage":false,"MobilePortraitImage":false,"MobilePortraitMode_aspect_ratio_3.5":false,"Images_aspect_ratio_4.3":false},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.0 - 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